Chimeric antigen receptor T cells (also known as CAR T cells) are T cells that have been genetically engineered to produce an artificial T cell receptor for use in immunotherapy.
Chimeric antigen receptors (CARs, also known as chimeric immunoreceptors, chimeric T cell receptors or artificial T cell receptors) are artificial receptor proteins that have been genetically engineered to give T cells the new ability to target a specific protein on tumor cells. The receptors are chimeric because they combine the antigen-binding domain of a monoclonal antibody and the T cell activating domain of CD3ζ protein into a single receptor.
BiCell Scientific’s CAR-T Cell Service provides customized pre-clinical CAR-T Cell generation and validation services including monoclonal antibody development, chimeric antigen receptor cloning, lentivirus packaging, mouse T cell transduction, and in vitro testing of CAR-T cells.
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