Anti-HDAC3 antibody is validated on mouse tissue and recommended for immunofluorescence labeling, IHC, or western blot of materials from human and rodent tissues.
Histone deacetylase 3 is an enzyme that is encoded by the HDAC3 gene in human. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. HDAC3 belongs to the histone deacetylase/acuc/apha family. HDAC3 has histone deacetylase activity and represses transcription when tethered to a promoter. HDAC3 also participates in the regulation of transcription through its binding with the zinc-finger transcription factor YY1.
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