Anti-KDM2A (JHDM1A) antibody is validated on mouse tissue and recommended for immunofluorescence labeling, IHC, or western blot of materials from human and rodent tissues.
Lysine-specific demethylase 2A (KDM2A), also known as F-box and leucine-rich repeat protein 11 (FBXL11) is an enzyme that is encoded by the KDM2A gene in human. KDM2A is a member of the superfamily of alpha-ketoglutarate-dependent hydroxylases. KDM2A is a histone H3 lysine 36 demethylase enzyme. The enzymatic activity of KDM2A relies on a conserved JmjC domain in the N-terminus of the protein that co-ordinates iron and alphaketoglutarate to catalyze demethylation via a hydroxylation based mechanism.
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