Anti-LLGL2 (LGL2) antibody is validated on mouse tissue and recommended for immunofluorescence labeling, IHC, or western blot of materials from rodent and human tissues.
Lethal(2) giant larvae protein homolog 2 is encoded by the LLGL2 gene in human. The lethal(2) giant larvae protein of Drosophila plays a role in asymmetric cell division, epithelial cell polarity, and cell migration. In fly, the protein’s ability to localize cell fate determinants is regulated by the atypical protein kinase C (aPKC). In human, LLGL2 interacts with aPKC-containing complexes and is cortically localized in mitotic cells.
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