Anti-OCT4 (OCT3 or POU5F1) antibody is validated on mouse tissue and recommended for immunofluorescence labeling, IHC, or western blot of materials from rodent and human tissues.
OCT4 (octamer-binding transcription factor 4), also known as OCT3 or POU5F1 (POU domain, class 5, transcription factor 1), is a protein that is encoded by the POU5F1 gene in human. OCT4 is a transcription factor containing a POU homeodomain and playing a key role in stem cell pluripotency. OCT4 binds to an octamer motif in DNA, a particular sequence of AGTCAAAT to regulate gene expression. OCT4 is one of the transcription factors used to create induced pluripotent stem cells (iPSCs), together with Sox2, Klf4 and c-Myc.
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