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Piezo2 antibody labeling of mouse retina

Piezo2 antibody labeling of mouse retina

Piezo2 proteins are found in the neural synapses of the OPL in the mouse retina. ONL: outer nuclear layer; OPL: outer plexiform layer; INL: inner nuclear layer; IPL: inner plexiform layer; GCL: ganglion cell layer.

Piezo2 Antibody

$155.00 – $435.00

Item Cat No.: 20712

Antibody: Rat Piezo2 Polyclonal Antibody

Concentration: 0.25 mg/ml purified IgG

Application: Validated by immunofluorescence labeling (1:100)

Reactivity: Human, mouse, rat

Anti-Piezo2 antibody is validated on mouse tissue and recommended for immunofluorescence labeling, IHC, or western blot of materials from rodent and human tissues.

Optional Blocking Peptide

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Anti-Piezo2 antibody is validated on mouse tissue and recommended for immunofluorescence labeling, IHC, or western blot of materials from human and rodent tissues.

Piezo-type mechanosensitive ion channel component 2, abbreviated for Piezo2, is encoded by the PIEZO2 gene in human. Piezo2 plays a role in rapidly adapting mechanically activated (MA) currents in somatosensory neurons. Mutations in PIEZO2 are linked to Gordon syndrome (distal arthrogryposis type 3), Marden-Walker syndrome and Arthrogryposis (Distal Arthrogryposis Type 5).

Host/Isotype: Rat/IgG

Class: Polyclonal

Immunogen: Synthetic peptide (13-aa) derived from the C-terminal cytoplasmic region of human Piezo2 protein

Species homology of immunogen: Synthetic peptide sequence is identical to mouse or rat sequence

Conjugation: Unconjugated

Purification: Affinity chromatography

Storage buffer: PBS, pH 7.2, 0.1% sodium azide

Storage condition: –20°C

For Research Use Only. Not for use in clinical diagnostics.

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"I am really impressed with your approach. We tried multiple times previously to create monoclonal and polyclonal antibodies to claudin-2 and MLCK1. We have had limited success generating polyclonals and no success generating monoclonals. You have generated outstanding monoclonals to both. I look forward to continuing to work with you."

Jerrold R. Turner, M.D., Ph.D.

Brigham and Women’s Hospital | Harvard Medical School

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Julie Craft Van De Weghe, PhD

School of Medicine | University of Washington

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Divyesh Joshi, PhD

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