Anti-TGFBR2 (TGFR-2) antibody is validated on mouse tissue and recommended for immunofluorescence labeling, IHC, or western blot of materials from human and rodent tissues.
Transforming growth factor beta receptor II is a transmembrane TGF beta receptor protein that is encoded by the TGFBR2 gene in human. TGFBR2 has a protein kinase domain and can form a heterodimeric complex with TGF-beta receptor type-1. Mutations in this gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors.
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