Anti-Alpha-catenin (Ctnna1) antibody is validated on mouse tissue and recommended for immunofluorescence labeling, IHC, or western blot of materials from rodent and human tissues.
Alpha-catenin is encoded by the CTNNA1 gene in human. Alpha-catenin belongs to a protein family known as catenins.
Catenins are the linker proteins that connect adherens junction to the underlying cytoskeleton. Catenins also form the plaque of adherens junction. Alpha-catenin is known to interact with beta-catenin, vinculin, and alpha-actinin.
Alpha-catenin is widely expressed in epithelial and endothelial tissues.
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