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CACNA1C (Cav1.2) antibody

$99.00$295.00

Item Cat No.: 11042

Antibody: Rabbit CACNA1C (Cav1.2) Polyclonal Antibody

Concentration: 0.25 mg/ml purified IgG

Application: Validated by immunofluorescence labeling (1:100)

Reactivity: Human, mouse, rat

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Anti-CACNA1C (Cav1.2) antibody is validated on mouse tissue and recommended for immunofluorescence labeling, IHC, or western blot of materials from rodent and human tissues.

Calcium channel, voltage-dependent, L type, alpha 1C subunit (also known as Cav1.2) is a protein that is encoded by the CACNA1C gene in human. The alpha-1 subunit consists of 24 transmembrane segments and forms the pore through which ions pass into the cell. The calcium channel consists of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Cav1.2 is widely expressed in the smooth muscle, pancreatic cells, fibroblasts, and neurons. In the heart, Cav1.2 mediates L-type currents, which causes calcium-induced calcium release from the ER Stores via ryanodine receptors.

Host/Isotype: Rabbit/IgG

Class: Polyclonal

Immunogen: Synthetic peptide (17-aa) derived from the N-terminal region of mouse Cav1.2 protein

Species homology of immunogen: Synthetic peptide sequence is identical to rat sequence (showing 94.1% homology to human sequence)

Conjugation: Unconjugated

Purification: Affinity chromatography

Storage buffer: PBS, pH 7.2, 0.1% sodium azide

Storage condition: –20°C


For Research Use Only. Not for use in clinical diagnostics.

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