Anti-Claudin-14 (CLDN14) antibody is validated on mouse tissue and recommended for immunofluorescence labeling, IHC, or western blot of materials from rodent and human tissues.
Claudin-14 is a protein that is encoded by the CLDN14 gene in human. Claudin-14 belongs to the Claudin protein superfamily.
Claudins are tetraspan proteins making the tight junction. Claudins have four transmembrane domains, two extracellular loops (ECLs: ECL1 and ECL2), amino- and carboxyl-terminal cytoplasmic domains, and a short cytoplasmic motif.
Claudin-14 is expressed by the sensory hair cells in the organ of Corti. Mutations in Claudin-14 cause autosomal recessive deafness 29 (DFNB29) (OMIM 614035).
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