Anti-Collagen alpha-5 (IV) (Col4a5) antibody is validated on mouse tissue and recommended for immunofluorescence labeling, IHC, or western blot of materials from rodent and human tissues.
Collagen, type IV, alpha-5 chain is a protein that is encoded by the COL4A5 gene in human. Type IV collagen is the major structural component of the glomerular basement membrane (GBM).
Type IV collagen is a triple helical oligomer formed by 3 alpha chain molecules. Type IV collagen is found in the ear, the eye, and the kidney.
Mutations in COL4A5 cause a hereditary renal disease known as X-linked Alport syndrome (OMIM 303630).
Reviews
There are no reviews yet.