Anti-Klotho (KL) antibody is validated on mouse tissue and can be used for immunofluorescence labeling, IHC, or western blot of materials from rodent and human tissues.
Klotho (KL) or α-Klotho is encoded by the KL gene in human. Klotho is a type-I membrane protein that is related to β-glucuronidases. Klotho can exist in a membrane-bound form or a (hormonal) soluble, secreted form. Proteases convert the membrane-bound form into the secreted form. The expression level of Klotho is associated with the development of chronic kidney failure.
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