Anti-TGFBR1 (TGFR-1) antibody is validated on mouse tissue and recommended for immunofluorescence labeling, IHC, or western blot of materials from human and rodent tissues.
Transforming growth factor beta receptor I is a membrane-bound TGF beta receptor protein that is encoded by the TGFBR1 gene in human. TGFBR1 is a serine/threonine protein kinase. It transduces the TGF-beta signal from the cell surface to the cytoplasm. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS).
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