Anti-VEGFR1 (FLT1) antibody is validated on mouse tissue and recommended for immunofluorescence labeling, IHC, or western blot of materials from rodent and human tissues.
Vascular endothelial growth factor receptor 1 (VEGFR1), also known as fms related receptor tyrosine kinase 1 (FLT1), is encoded by the FLT1 gene in human. VEGFR1 is a receptor tyrosine kinase (RTK) that contains an extracellular ligand-binding region with seven immunoglobulin (Ig)-like domains, a transmembrane domain, and a tyrosine kinase (TK) domain within the cytoplasmic domain. VEGFR1 binds to VEGFR-A, VEGFR-B and placental growth factor and plays an important role in angiogenesis and vasculogenesis. Expression of VEGFR1 is found in vascular endothelial cells, placental trophoblast cells and peripheral blood monocytes.
Reviews
There are no reviews yet.