Anti-CEP57 antibody is validated on mouse tissue and recommended for immunofluorescence labeling, IHC, or western blot of materials from rodent and human tissues.
Centrosomal protein of 57 kDa (CEP57) is encoded by the CEP57 gene in human. CEP57 localizes to the centrosome and has a function in microtubular stabilization. The N-terminal half of CEP57 is required for its centrosome localization and for its polymerization, and the C-terminal half is required for nucleating, bundling and anchoring microtubules to the centrosomes. CEP57 is crucial for maintaining correct chromosomal number during cell division. Mutations in this gene cause an autosomal recessive disorder, mosaic variegated aneuploidy syndrome.
Reviews
There are no reviews yet.