Annotation of mouse epithelia

The skin, or integument, consists of two major layers: the epidermis, composed of stratified squamous epithelium that is keratinized, and the dermis, composed of connective tissue.

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E-cadherin proteins label the epithelial cell junctions in the epidermis of the skin from a mouse embryo at E15.5. Ep, epidermis; De, dermis; HF, hair follicle

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High-magnification view of the epithelium in the epidermis. The cell layer that occupies the deepest location is the stratum basale (SB), composed of cuboidal basal cells.

The kidney is an epithelial tissue composed of the uriniferous tubules. The uriniferous tubules consists in several segments, e.g., the proximal tubule, the loop of Henle, the distal tubule and the collecting duct.

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E-cadherin proteins label the epithelial cell junctions in the uriniferous tubules of the kidney from a mouse embryo at E15.5. UB, ureteric bud; CD, collecting duct.

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High-magnification view of the epithelium in the kidney. Ep, epithelium; Str, stroma.

The lung is made of a type of epithelial structure known as alveolus. The alveolus is lined with the alveolar cells, extremely thin squamous epithelial cells. Groups of alveoli cluster into alveolar sacs.

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E-cadherin proteins label the epithelial cell junctions of the alveolar cells in the lung from a mouse embryo at E15.5. B, bronchiole; AD, alveolar ducts.

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High-magnification view of the alveolar epithelium in the lung. AS, alveolar sacs.

The gut is lined with simple columnar epithelium, which serves two main functions: absorbing nutrients and restricting the entry of harmful substances. As part of its protective role, the gut epithelium forms a mucosal barrier.

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E-cadherin proteins label the epithelial cell junctions of the mucosa in the gut from a mouse embryo at E15.5. Muc, mucosa; SubM, submucosa.

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High-magnification view of the intestinal epithelium in the mucosa. Ep, epithelium; Str, stroma.

The liver is a glandular tissue made of a series of ducts of increasing diameter and complexity, beginning with the bile canaliculi between individual hepatocytes and ending with the common bile duct.

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E-cadherin proteins label the epithelial cell junctions of the hepatocytes in the liver from a mouse embryo at E15.5. CV, central vein (terminal hepatic venule).

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High-magnification view of the hepatocytes in the liver. BC, bile canaliculus.

The pancreas is an elongated extramural digestive organ made of a compound tubuloacinar network and the highly vascularized islets of epithelioid tissue, known as the islets of Langerhans.

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E-cadherin proteins label the cell junctions of the tubuloacinar epithelia in the pancreas from a mouse embryo at E15.5. InD, intralobular duct.

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High-magnification view of the acinar epithelium in the pancreas. CC, centroacinar cells.