Protein Atlas in Cell and Tissue

Delineating cell lineage in the collecting duct of mouse kidney

Differentiating principal cell from intercalated cell Expand The collecting duct in the kidney consists in three types of cells, principal cells, alpha-intercalated cells and beta-intercalated cells. The principal cells are primarily responsible for salt and water transport while alpha- and beta-intercalated cells are responsible for acid-base transport. Figure legend Anti-Aqp2 antibody labels the luminal membrane […]

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Annotation of the mitochondrion in mouse brain

The cerebral cortex Expand The mitochondrion shows a pattern of punctate appearance in the cytoplasm of the cell body in the neurons of the cerebral cortex. Figure legend TOMM20 antibody labels the mitochondria in the pyramidal neurons of the cerebral cortex in the mouse brain. The hippocampus Expand The mitochondrion shows a pattern of punctate […]

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Annotation of endoplasmic reticulum in mouse tissues

The skin Expand The ER in the epidermal cells shows a pattern of perinuclear network that is continuous with the nuclear membrane. Figure legend Calreticulin antibody labels the ER in the epithelium of the skin from a mouse embryo at E12.5. The liver Expand The ER in the hepatocytes shows a pattern of perinuclear network […]

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Annotation of the Golgi apparatus in mouse tissues

The gut Expand The Golgi apparatus in the gut shows a pattern of longitudinal network that facilitates polarized vesicle transport. Figure legend GRASP65 antibody labels the Golgi apparatus in the epithelium of the primordial gut from a mouse embryo at E12.5. The skin Expand The Golgi apparatus in the epidermal cells shows a pattern of […]

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"I am really impressed with your approach. We tried multiple times previously to create monoclonal and polyclonal antibodies to claudin-2 and MLCK1. We have had limited success generating polyclonals and no success generating monoclonals. You have generated outstanding monoclonals to both. I look forward to continuing to work with you."

Jerrold R. Turner, M.D., Ph.D.

Brigham and Women’s Hospital | Harvard Medical School

"The polyclonal antibody you generated for KIAA0408 is stunning! KIAA0408 is a novel cilium molecule that has never been studied. So, clearly there will be a lot of demand for it as we have discovered a very interesting finding and the story will be published in a high impact journal. I am strongly inclined to generate monoclonal antibody for this protein too and we should think about patenting it."

Univ.-Prof. Jay Gopalakrishnan PhD

Heinrich-Heine-Universität | Universitätsklinikum Düsseldorf

"Your ARL13B antibody works beautifully!!! We’re so happy to have a cilia-specific antibody made in rat! I can send you high resolution images to be posted on your website."

Julie Craft Van De Weghe, PhD

School of Medicine | University of Washington

"The assay is a homophilic interaction mediated cell adhesion on purified protein (in this case, immobilized purified Pcdhga9 to Pcdhga9 expressed on cell surface). Compared to control, cell adhesion is reduced in the presence of Pcdhga9 monoclonal antibody supernatants!"

Divyesh Joshi, PhD

School of Medicine | Yale University

"The rabbit hybridoma supernatants of anti-APOBEC3 project are tested positive by ELISA, and we are very happy about it! We previously tried a company, Abclone. Their Project "A" has immune response that is <10,000 titer in antiserum, which would explain why there is no positive mAb after fusion. Their project "B" didn't have any immune response in rabbit."

Harshita B Gupta, PhD.

School of Medicine | UT Health San Antonio

"We have tested anti mouse T cell antiserum samples from both rabbits you sent to us.

They worked very well! Thank you!"

Victoria Gorbacheva, PhD.

School of Medicine | Cleveland Clinic

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