Anti-WNK4 antibody is validated on mouse tissue and recommended for immunofluorescence labeling, IHC, or western blot of materials from rodent and human tissues.
WNK lysine deficient protein kinase 4 or WNK4 is an enzyme that is encoded by the WNK4 gene in human.
WNK4 is highly expressed in the kidney tubules where it regulates the salt reabsorption via various ion channels. WNK4 plays a vital role in the regulation of extracellular fluid volume and blood pressure.
Mutations in WNK4 cause a dominant form of pseudohypoaldosteronism type 2 (PHA-II), also known as Gordon syndrome (OMIM 614491).
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